Protein Purification
Cayman Chemical FAK InhIbItr 14 50mg
A direct inhibitor of FAK1 autophosphorylation, blocking phosphorylation of Y397 (IC50 = 1 μM); no known significant effect on the activity of a range of other kinases; promotes cell detachment and inhibits cell adhesion of cells in culture; blocks tumor growth in vivo
AdipoGen Listeria mp60 recHis
Protein. Listeria monocytogenes p60 aa 1-484 is fused at the C-terminus to a His-tag. Source E. coli. Endotoxin content <1EU/µg purified protein LAL test Lonza. Liquid. 0.2µm-filtered solution in PBS, pH 7.2. Purity >90% SDS-PAGE. Listeria monocytogenes is a intracellular bacterium that is the causative agent of Listeriosis. It is one of the most virulent foodborne pathogens. Listeria species are known to secrete a 60kDa protein collectively termed p60, which is encoded by the "iap" invasion-associated-protein gene and secreted in large quantities into the growth media. p60 is a highly immunogenic murein hydrolase that is essential for cell division.
BPS Bioscience Inc PD-1 Lentivirus, 2 x 500 μl, ≥10^7 TU/ml, VSV-G pseudotyped, CMV promoter, Blasticidin selection marker, HIV-based, self-inactivating (SIN) vector
The PD-1 Lentivirus is a replication-incompetent, HIV-based, VSV-G pseudotyped lentiviral particle designed for efficient transduction of human PD-1 into various mammalian cell types. It allows the delivery of the human Programmed Death Protein 1 (PD-1) gene under the CMV promoter, along with a Blasticidin selection marker, suitable for creating stable cell lines. This product is instrumental in PD-1 biology research and the development of PD-1-targeted therapeutics.
- VSV-G pseudotyping enables efficient transduction of nearly all mammalian cell types.
- Provides stable expression of human PD-1 for consistent experimental results.
- Blasticidin resistance gene facilitates selection and enrichment of transduced cells.
- Self-inactivating (SIN) lentivector enhances safety by preventing further viral replication.
- Ideal for investigations into PD-1 antibodies and therapeutics for cancer and immune-related diseases.
AKADEUM LIFE SCIENCES INC Akadeum MOUSE B CELL ISOLATION KIT
The Mouse B Cell Isolation Kit leverages flotation to deliver a high purity population of murine B cells that are ready for downstream use. The BACS™ Microbubble workflow is exceptionally gentle on cells, helping to maintain the health and physiology of B cells during enrichment. No magnet required. The Mouse B Cell Isolation Kit uses a negative selection method to remove unwanted cell populations and effectively enrich B Cells. Unwanted cells are labeled with biotinylated antibodies targeting CD3, CD4, CD8a, CD11b, CD11c, CD49b, CD90.2, CD105, Gr1, Ter119. BACS™ Microbubbles are added to the sample and bind to the antibody-labeled cells. Microbubbles bound to the undesired cells quickly and gently float the undesired cells to the surface. B cells, the cells of interest, are pelleted through centrifugation. Capacity: 1 billion cells.
Hampton Research HR2-982-25/PEGRx 1 #25 (C1), 185 ml - 0.1 M Sodium citrate tribasic dihydrate pH 5.0, 30% v/v Jeffamine ED-2001 pH 7.0
HR2-982-25/PEGRx 1 #25 (C1), 185 ml - 0.1 M Sodium citrate tribasic dihydrate pH 5.0, 30% v/v Jeffamine ED-2001 pH 7.0. Please note items from this supplier are non-returnable.
ACROBiosystems Anti-Human IgG-coupled Magnetic Beads (recommended for MPCLIA)
The Anti-Human IgG-coupled Magnetic Beads are 2.8 µm superparamagnetic particles covalently coupled to a highly affinity Monoclonal mouse anti-human IgG antibody. The beads can be used to capture the human IgG in Chemiluminescence procedures.The antibody reacts with the Fc portion of human IgG heavy chain but not with the Fab portion of human IgG. No antibody was detected against human IgM or IgA, or against non-immunoglobulin serum proteins. The antibody has been tested by ELISA and/or solid-phase adsorbed to ensure minimal cross-reaction with mouse, cynomolgus and bovine serum proteins, but it is not sure if the product cross-react with immunoglobulins from other species.The Anti-Human IgG-coupled Magnetic Beads is easy to capture the human IgG, and the bounded antibody have no activity lost, this ready to use products could greatly save your protein coupling time and hassle, and help us get the best performance and highly reproducible results.
Cayman Chemical PTP InhIbItr I 100mg
A SHP-1 and PTP1B inhibitor (Kis = 43 and 42 µM for the SHP-1 catalytic domain and full-length PTP1B, respectively); inhibits endothelial cell network formation of HUVECs cultured with normal human dermal fibroblasts (IC50 = 3.7 µM); has been used in the synthesis of compounds with antibacterial, antifungal, fungicidal, and anticancer activities
Biolegend MojoSortTM Mouse F4/80 Selec
MojoSort™ Mouse F4/80 Selection Kit Reactivity: Mouse; Apps: Cell Sep - Pos; Size: 10 tests
Genscript Corporation CD8 alpha/CD8A His Mouse
CD8 alpha enhances the responses of antigen-specific CTL activated through TCR through binding MHC class I favoring lipid raft partitioning of TCR and inducing intracellular signaling CD8 alpha is also found on dendritic cells and rat macrophages but whether CD8 alpha enhances responses of a partner receptor like TCR to activate these cells is not known
Cayman Chemical Syk InhIbItr II 500ug
A cell-permeable, selective, and reversible inhibitor of Syk (IC50 = 41 nM); prevents FcεRI-mediated 5-HT release in RBL-2H3 cells in vitro (IC50 = 460 nM) and inhibits passive cutaneous anaphylaxis reactions in mice (ID50 = 13.2 mg/kg, s.c.)
Sigma Aldrich Fine Chemicals Biosciences Sephadex(R) G-25 Medium Cytiva, 17-0033-01, pack of 100 g | 1ML
Sephadex(R) G-25 Medium Cytiva, 17-0033-01, pack of 100 g | 1ML
Cayman Chemical JAK2 InhIbItr V 10mg
A selective inhibitor of the autophosphorylation of wild type and V617F mutant forms of JAK2, displaying IC50 values between 10 and 30 µM; blocks the proliferation of erythroleukemia cells and human hematopoietic progenitor cells expressing JAK2-V617F